Jianming Xu, Ph.D.
Affiliation: Department of Molecular and Cellular Biology, Baylor College of Medicine
TITLE OF TALK: The SRC-1–Twist1 Gene Regulation Axis in Breast Cancer Cell Plasticity and Metastasis
Jianming Xu received his BS, MS and PhD degrees from China West Normal University, Beijing Normal University and Clarkson University, respectively. After he accomplished his postdoctoral training in Baylor College of Medicine, Jianming has been a faculty member in the Department of Molecular and Cellular Biology (MCB) at the same medical school for 20 years. He is now a full professor in the Department of MCB and the Director of Genetically Engineered Mouse Core at Baylor College of Medicine. Jianming has trained more than 10 PhD graduate students and more than 30 postdoctoral researchers and published 165 peer-reviewed papers. Jianming was the first to use knockout and transgenic mouse models to study the physiological function of nuclear receptor coactivators and their roles in mammary gland tumorigenesis and metastasis. Jianming’s current research is focused on elucidating the roles and mechanisms of transcriptional regulators including nuclear receptors, transcriptional coregulators and EMT-driving transcription factors in the origin, progression, plasticity and metastasis of steroid hormone-promoted cancer cells.