Valerie LeBleu is an Assistant Professor in the Department of Cancer Biology at the University of Texas MD Anderson Cancer Center.
Tentative title: “Snail-ing down fibrosis”
Dr. LeBleu received her Ph.D. from Harvard, and is a graduate of the Leder Medical Sciences Program. She is the recipient of the Ryan Fellowship Award and the Wilson S. Stone Award. Her laboratory studies the mechanisms underpinning tumor host responses to control cancer metastasis, and emphasizes on tumor vascular biology, tissue fibrosis, and its impact on the metabolic adaptation of cancer cells. Ongoing work focus on the impact of remodeling tumor vasculature on cancer immunity, and the impact of pro-metastatic metabolic adaptation of cancer cells in response to the dynamically evolving tumor stroma. Her studies aim to bridge concepts of cellular plasticity and cellular adaptation to stress from tissue fibrosis and remodeling into the limelight of metastasis research and tumor microenvironment. Dr. LeBleu served a member of the NCI tumor microenvironment network steering committee.